Emma Ahlqvist

Sep 7, 2023 | nature.com | Alessia Faggian |Alessia David |Reedik Mägi |Emma Ahlqvist |Gudmar Thorleifsson |Robert Scott | +37 more

AbstractConventional measurements of fasting and postprandial blood glucose levels investigated in genome-wide association studies (GWAS) cannot capture the effects of DNA variability on ‘around the clock’ glucoregulatory processes. Here we show that GWAS meta-analysis of glucose measurements under nonstandardized conditions (random glucose (RG)) in 476,326 individuals of diverse ancestries and without diabetes enables locus discovery and innovative pathophysiological observations.

Jun 8, 2023 | nature.com | Alice Williamson |Anne Jackson |Mette Andersen |Thomas Buchanan |Lee-Ming Chuang |Ren-Hua Chung | +43 more

Author notesThese authors jointly supervised this work: Karen L. Mohlke, Eleanor Wheeler, Stephen O’Rahilly, Daniel J. Fazakerley,Claudia Langenberg. Authors and AffiliationsMRC Epidemiology Unit Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UKAlice Williamson, Jian’an Luan, Nicholas J.

May 3, 2023 | nature.com | Roderick C. Slieker |Eleni Georgiadou |Giuseppe Giordano |Emma Ahlqvist |Ashfaq Ansari Ali |Karina Banasik | +22 more

Discovery cohorts Summary statistics of lipidomic, proteomic and metabolomic data is available from a Shiny dashboard available from: https://rhapdata-app.vital-it.ch. The generated metabolomic, lipidomic and proteomic data in DCS, GoDARTS and ANDIS are considered sensitive patient data and can therefore not be publicly available in compliance with the European privacy regulations governed by GDPR and according to limitations included in the informed consents signed by the study participants.