Emmanuelle Genoyer

2 months ago | cell.com | Emmanuelle Genoyer |Jonathan Wilson |Joshua Ames |Caleb Stokes |Dante Moreno |Noa Etzyon | +2 more

Keywords West Nile virus RIG-I RIG-I-like receptors innate immunity antiviral response Introduction Flaviviruses are a global threat to public health, placing billions at risk of infection and causing over 400 million disease cases per year worldwide.1 The emerging neurotropic flavivirus, West Nile virus (WNV), is the leading cause of arboviral infections in the United States, with recurrent annual outbreaks, and poses an ever-expanding hazard as its vector range increases.2 During WNV...

Dec 19, 2024 | science.org | Nandan S. Gokhale |Russell K Sam |Kim Y. Somfleth |Daphnee M Marciniak |Julian Smith |Emmanuelle Genoyer | +9 more

Supplementary MaterialsMDAR Reproducibility ChecklistReferences and notes1J. Rehwinkel, M. U. Gack, RIG-I-like receptors: Their regulation and roles in RNA sensing. Nat. Rev. Immunol. 20, 537–551 (2020). 2R. Savan, M. Gale Jr., Innate immunity and interferon in SARS-CoV-2 infection outcome. Immunity 56, 1443–1450 (2023). 3Y. J. Crow, J.-L. Casanova, Human life within a narrow range: The lethal ups and downs of type I interferons. Sci. Immunol. 9, eadm8185 (2024). 4H. Kato, O. Takeuchi, S. Sato, M. Yoneyama, M.