Erik H. Klontz

Oct 23, 2024 | mdpi.com | Erik H. Klontz |Isaac Solomon |Navid Chowdhury |Nolan Holbrook

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Feb 7, 2024 | nejm.org | Edward Ryan |Marc D. Succi |Molly L. Paras |Erik H. Klontz

This article is available to subscribers. Subscribe now. Already have an account? Sign in Case Records of the Massachusetts General HospitalFree PreviewList of authors. February 8, 2024N Engl J Med 2024; 390:549-556 DOI: 10.1056/NEJMcpc2309382Richard C. Cabot, Founder, Eric S. Rosenberg, M.D., Editor, David M. Dudzinski, M.D., Associate Editor, Meridale V. Baggett, M.D., Associate Editor, Kathy M. Tran, M.D., Associate Editor, Dennis C.

Sep 25, 2023 | jbc.org | Erik H. Klontz |Juliet O. Obi |Gabrielle Glendening |Dorothy Beckett

AbstractToll-like and Interleukin-1/18 receptor resistance (TIR) domain-containing proteins function as important signaling and immune regulatory molecules. TIR domain-containing proteins identified in eukaryotic and prokaryotic species also exhibit NAD+ hydrolase activity in select bacteria, plants, and mammalian cells.