Eun Seon Chung

Nov 14, 2024 | nature.com | Eun Seon Chung |Ariel Amir

AbstractDifficulties in antibiotic treatment of Mycobacterium tuberculosis (Mtb) are partly thought to be due to heterogeneity in growth. Although the ability of bacterial pathogens to regulate growth is crucial to control homeostasis, virulence and drug responses, single-cell growth and cell cycle behaviours of Mtb are poorly characterized.

Oct 28, 2024 | microbiologyresearch.org | Ji-Young Lee |Ji-young Lee |Eun Seon Chung |Yuxin Peng |Byeong Seob Oh

Purpose. It is known that the arnB (or pmrH) gene encoding uridine 5′-(beta-1-threo-pentapyranosyl-4-ulose diphosphate) aminotransferase plays a critical role in colistin resistance in Pseudomonas aeruginosa through the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to lipid A. In this study we attempted to obtain a colistin-resistant mutant from an arnB-deleted mutant through exposure to colistin. Methodology.