Eva Barcelona-Estaje

Oct 11, 2024 | nature.com | Eva Barcelona-Estaje |Aleixandre Rodrigo-Navarro |Matthew Dalby |Pere Roca-Cusachs |Marco Cantini

AbstractMesenchymal stem cells (MSCs) interact with their surroundings via integrins, which link to the actin cytoskeleton and translate physical cues into biochemical signals through mechanotransduction. N-cadherins enable cell-cell communication and are also linked to the cytoskeleton. This crosstalk between integrins and cadherins modulates MSC mechanotransduction and fate.