Farhana Alam

Oct 4, 2023 | microbiologyresearch.org | Farhana Alam |Hannah Pugh |Christopher Connor |Pauline Siasat

Introduction. We are becoming increasingly reliant on the effectiveness of biocides to combat the spread of Gram-negative multi-drug-resistant (MDR) pathogens including Klebsiella pneumoniae . It has been shown that chlorhexidine exposure can lead to mutations in the efflux pump repressor regulators SmvR and RamR but the contribution of each individual efflux pump to biocide tolerance is unknown. Hypothesis.