Hannah Pugh

Sep 23, 2024 | msn.com | Dana Meredith |Hannah Pugh

Sep 18, 2024 | msn.com | Carrie Madormo |Hannah Pugh

Aug 1, 2024 | biorxiv.org | Hannah Pugh |Elizabeth Darby |Leah J. Burgess |Abigail L Colclough

AbstractTripartite resistance-nodulation-division (RND) efflux pumps confer multidrug resistance (MDR) in Gram-negative bacteria and are critical for many physiological functions including virulence and biofilm formation. The common laboratory strain of E. coli, K-12 MG1655 has six recognised RND transporters participating in tripartite pump formation (AcrB, AcrD, AcrF, CusA, MdtBC, and MdtF). However, by studying >20,000 E. coli genomes we show that E.

Oct 4, 2023 | microbiologyresearch.org | Farhana Alam |Hannah Pugh |Christopher Connor |Pauline Siasat

Introduction. We are becoming increasingly reliant on the effectiveness of biocides to combat the spread of Gram-negative multi-drug-resistant (MDR) pathogens including Klebsiella pneumoniae . It has been shown that chlorhexidine exposure can lead to mutations in the efflux pump repressor regulators SmvR and RamR but the contribution of each individual efflux pump to biocide tolerance is unknown. Hypothesis.

Sep 9, 2023 | thedailymeal.com | Hannah Pugh

Who's ever heard of an ice cream fork? This unique utensil happens to be the traditional cutlery of choice for ice cream sundaes. Yet, distinctions to its modern-day equivalent, the spork, are virtually non-existent. Although the two utensils look the same and are capable of the same things, their difference is simply in their history and their names. So, what is an ice cream fork? A utensil with the round curve of a spoon and shallow tines at the tip.