Fariba Dehghani

Aug 7, 2023 | onlinelibrary.wiley.com | Helen Power |Biomolecular Engineering The |Peter Valtchev |Fariba Dehghani

3.10 Antibiotics Azithromycin and roxithromycin are antibiotics that have shown some senolytic activity in human cells. This was revealed in a screen of 15 approved antibiotics in a model featuring BrdU-treated MRC-5 and BJ fibroblasts (Ozsvari et al., 2018). Moreover, the antibiotic nigericin was found to induce senolysis in several cell types (Deryabin et al., 2022). This is consistent with prior reports indicating it could disrupt various homeostatic systems in mammalian cells.

Jul 27, 2023 | cell.com | Sepehr Talebian |Fariba Dehghani |Paul Weiss

California NanoSystems Institute, University of California, Los Angeles, Los Angeles, CA 90095, USADepartment of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA 90095, USADepartment of Bioengineering, University of California, Los Angeles, Los Angeles, CA 90095, USADepartment of Materials Science and Engineering, University of California, Los Angeles, Los Angeles, CA 90095, USA