Fischer von Weikersthal

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Spirituality in oncology: relations between spirituality, its facets and psychological and demographic factors in cancer patients in Germany

Feb 7, 2024 | karger.com | Fischer von Weikersthal

Introduction: Cancer diagnoses are constantly increasing in clinical practice. Therefore, more and more patients are interested in how they can actively participate in the process of treatment. Spirituality represents a hidden issue of the population, which counts as a branch of complementary and alternative treatment.
Negative hyperselection of resistance mutations for panitumumab maintenance in RAS wild-type metastatic colorectal cancer (PanaMa phase II trial, AIO KRK 0212).

Jan 30, 2024 | aacrjournals.org | Charité Universitätsmedizin |Fischer von Weikersthal |Charité Universitätsmedizin Berlin |Charité-Universitätsmedizin Berlin

Background: We evaluated additional mutations in RAS wild-type (WT) metastatic colorectal cancer (mCRC) as prognostic and predictive biomarkers for the efficacy of added panitumumab to a FU/FA maintenance as pre-specified analysis of the randomized PanaMa trial. Methods: Mutations (MUT) were identified using targeted next generation sequencing (NGS; Illumina Cancer Hotspot Panel v2) and immunohistochemistry.

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