Florian Kipfmueller

2 months ago | respiratory-research.biomedcentral.com | De Vadder |Bartolomeo Bo |Neil Patel |Stefan Holdenrieder |Andreas Mueller |Florian Kipfmueller | +3 more

We performed a prospective single-center (University Hospital of Bonn) subgroup analysis of CDH newborns born between 2014 and 2022, who were initially enrolled in the “Biomarker forOutcomePredictionin Neonates withCongenital Diaphragmatic Hernia” (BIOPTIC) study (Clinical trial registration with German Clinical Trial Register (DKRS), trial registration number: DKRS00034329; Registration date: 24.05.2024).

Jan 14, 2025 | nature.com | Florian Kipfmueller

The pathophysiology of perinatal asphyxia is remarkably complex, triggering a cascade of biochemical dysregulations across multiple systems.1,2 The distinctiveness of neonatal asphyxia lies in its timing, taking place during the vulnerable window of postnatal adaptation where changes in blood oxygen levels play a pivotal role in pulmonary and cardiovascular transition.3 At the histological level, including the myocardium, hypoxia initiates VEGF overexpression, which activates angiogenic...

Dec 18, 2024 | onlinelibrary.wiley.com | Lennart Hale |Judith Leyens |Bartolomeo Bo |Clara Engel |Christoph Berg |Lukas Schroeder | +2 more

AUC area under the curve CDH congenital diaphragmatic hernia CLD chronic lung disease ECMO extracorporeal membrane oxygenation FiO2 fraction of inspired oxygen HI Horovitz Index MAP mean airway pressure NPV negative predictive value OI Oxygenation Index OSI Oxygen Saturation Index PaO2 partial pressure of arterial oxygenation PCO2 partial pressure of CO2 PH pulmonary hypertension PPV positive predictive value ROC receiver operating characteristics SaO2 oxygen saturation of the blood SpO2...

Jun 14, 2023 | onlinelibrary.wiley.com | Florian Kipfmueller |Joachim Schmitt |Hemmen Sabir |Bartolomeo Bo

Abstract Aims Extracorporeal membrane oxygenation (ECMO) is a widely used technique to support neonates with severe respiratory failure. Data on percutaneous, ultrasound-guided veno-venous (VV) ECMO cannulation in neonates is still scarce. Aim of this study was to describe our institutional experience with ultrasound-guided percutaneous, VV ECMO cannulation in neonates with severe respiratory failure.