Francesco Benedetti

Nov 4, 2024 | nature.com | Christoph Abe |Francesco Benedetti |Erlend Bøen |Katharina Brosch |Erick J. Canales-Rodriguez |Torbjørn Elvsåshagen | +34 more

AbstractAlthough specific risk factors for brain alterations in bipolar disorders (BD) are currently unknown, obesity impacts the brain and is highly prevalent in BD. Gray matter correlates of obesity in BD have been well documented, but we know much less about brain white matter abnormalities in people who have both obesity and BD.

Jun 7, 2024 | nature.com | Sara Poletti |Francesco Benedetti

AbstractMajor depressive disorder (MDD) and bipolar disorder (BD) are highly disabling illnesses defined by different psychopathological, neuroimaging, and cognitive profiles. In the last decades, immune dysregulation has received increasing attention as a central factor in the pathophysiology of these disorders.

Jan 10, 2024 | nature.com | Francesco Benedetti |Kathryn Cullen |Ian H. Gotlib |J Hamilton |Thomas Lancaster |Sara Poletti | +5 more

AbstractMachine learning (ML) techniques have gained popularity in the neuroimaging field due to their potential for classifying neuropsychiatric disorders. However, the diagnostic predictive power of the existing algorithms has been limited by small sample sizes, lack of representativeness, data leakage, and/or overfitting.