Francesco Bonella

Nov 14, 2024 | publications.ersnet.org | Cormac McCarthy |College Dublin |Francesco Bonella |Clairelyne Dupin

Guideline Or Statement | ERS Guidelines European Respiratory Society guidelines for the diagnosis and management of pulmonary alveolar proteinosis ArticleFigures & TablesInfo & Metrics

Nov 11, 2024 | respiratory-research.biomedcentral.com | Kakuhiro Yamaguchi |Shinichiro Ohshimo |Hiroshi Iwamoto |Shinjiro Sakamoto |Yasushi Horimasu |Takeshi Masuda | +7 more

This study included 171 patients with IPF (69 German and 102 Japanese patients). The median follow-up time was 29.9 months (12.0–44.8 months). The main characteristics of the patients are shown in Table 1. The median age was 68 years, and 139 of 171 patients (81.2%) were men. The Japanese cohort comprised more male patients with IPF than the German cohort.

Jan 4, 2024 | erj.ersjournals.com | Francesco Bonella

FootnotesConflict of interest: F. Bonella reports consulting fees from Boehringer Ingelheim, Sanofi, Savara Pharma and CSL Behring, lecture honoraria from Boehringer Ingelheim and Sanofi, travel support from Boehringer Ingelheim, AstraZeneca and Atyr, and advisory board participation with Boehringer Ingelheim, Sanofi and GSK, outside the submitted work.

Mar 16, 2023 | erj.ersjournals.com | Raphael Borie |Caroline Kannengiesser |Francesco Bonella |Bruno Crestani

IntroductionGenetic predisposition to pulmonary fibrosis is suggested by a 10-fold increase in disease prevalence in families of patients with a diagnosis of idiopathic pulmonary fibrosis (IPF) [1–3]. Initial studies of familial clustering of interstitial lung disease (ILD) led to the discovery of mutations in genes implicated in telomere homeostasis (telomere-related genes (TRGs)) and surfactant homeostasis (surfactant-related genes (SRGs)) (table 1 and ) [3, 4].