Francesco Comacchio

Jul 20, 2023 | frontiersin.org | Nose Diseases |Throat Diseases |Brian McKinnon |Francesco Comacchio

1. Introduction Idiopathic sudden sensorineural hearing loss (ISSNHL) was defined as a sudden hearing loss that occurs within 72 h, and pure tone audiometry results show a decline at least in the three adjacent frequencies (>30 dBHL) without any identifiable cause (1), which may lead to difficulty in speech recognition and sound localization, especially in noisy environments, and has a significant negative impact on the quality of life and mental status of patients (2–4).