Francisco Alejandro Lagunas-Rangel

Nov 17, 2024 | tandfonline.com | Francisco Alejandro Lagunas-Rangel

ABSTRACTCircular RNAs (circRNAs) exhibit a wide range of activities that allow them to participate in numerous cellular processes and make them relevant in a variety of diseases. In this regard, a key process in which circRNAs are involved, and which is the focus of this article, is DNA damage repair (DDR). This study aims to illustrate how circRNAs influence different DNA repair pathways, with particular emphasis on the underlying mechanisms.

Aug 16, 2024 | nature.com | Francisco Alejandro Lagunas-Rangel

AbstractHeterochronic parabiosis consists of surgically connecting the circulatory systems of a young and an old animal. This technique serves as a model to study circulating factors that accelerate aging in young organisms exposed to old blood or induce rejuvenation in old organisms exposed to young blood. Despite the promising results, the exact cellular and molecular mechanisms remain unclear, so this study aims to explore and elucidate them in more detail.

Nov 12, 2023 | mdpi.com | Francisco Alejandro Lagunas-Rangel |Michael Williams |Sifang Liao |Vladimir Trukhan

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