Franziska Knolle

Jun 8, 2023 | nature.com | Franziska Knolle |Roger Barker |Jimmy Lee |Siwei Liu |Graham K Murray |Juan Zhou

AbstractPsychotic symptoms occur in a majority of schizophrenia patients and in ~50% of all Parkinson’s disease (PD) patients. Altered grey matter (GM) structure within several brain areas and networks may contribute to their pathogenesis. Little is known, however, about transdiagnostic similarities when psychotic symptoms occur in different disorders, such as in schizophrenia and PD.

May 5, 2023 | frontiersin.org | Sophie Pauline |Franziska Knolle |Karl Friston |Joost Haarsma

Introduction Conceptualized as the “extended psychosis phenotype,” psychotic phenomena presumably exist on a dimension, ranging from manifest psychosis to mild subclinical psychotic-like experiences (PLEs) (1). PLEs involve unusual subjective experiences that resemble subtle psychotic symptoms but do not necessarily cause distress (2).