Franziska Wachter

Nov 22, 2023 | onlinelibrary.wiley.com | Franziska Wachter |Yana Pikman |Jacob Bledsoe |Malika Kapadia

1 INTRODUCTION Survival is dismal for the 40%–60% of children with myelodysplastic syndrome (MDS) who relapse post allogeneic hematopoietic cell transplantation (HCT).1-3 Strategies to decrease relapse risk includes use of cytoreduction prior to HCT or maintenance treatment after HCT, data on the utility of these approaches remains limited.4-12 Rapid withdrawal of immune suppression or use of donor lymphocyte infusion (DLI) can enhance the graft versus leukemia effect and achieve disease...