Frédéric Couture

Sep 14, 2023 | paperity.org | Amro H. Mohammad |Frédéric Couture |Isabelle Gamache |Owen Chen

PLOS ONE, Jul 2023 Phosphatase and tensin homolog (PTEN) mutation is common in prostate cancer during progression to metastatic and castration resistant forms. We previously reported that loss of PTEN function in prostate cancer leads to increased expression and secretion of the Prorenin Receptor (PRR) and its soluble processed form, the soluble Prorenin Receptor (sPRR). PRR is an essential factor required for proper assembly and activity of the vacuolar-ATPase (V-ATPase).

Jul 18, 2023 | journals.plos.org | Amro H. Mohammad |Frédéric Couture |Université de Sherbrooke |Isabelle Gamache

Loading metrics Open Access Peer-reviewedResearch Article AbstractPhosphatase and tensin homolog (PTEN) mutation is common in prostate cancer during progression to metastatic and castration resistant forms. We previously reported that loss of PTEN function in prostate cancer leads to increased expression and secretion of the Prorenin Receptor (PRR) and its soluble processed form, the soluble Prorenin Receptor (sPRR).

Jul 12, 2023 | niagarafallsreview.ca | Frédéric Couture

Montreal tourism operators have begun to feel the impact of the suspension of the only daily train between their city and New York City. “Summer is the busiest tourist season in Montreal. And between New York and Montreal, there is no rail alternative,” said Tourisme Montréal spokeswoman Aurélie de Blois.

Jul 12, 2023 | therecord.com | Frédéric Couture

Montreal tourism operators have begun to feel the impact of the suspension of the only daily train between their city and New York City. “Summer is the busiest tourist season in Montreal. And between New York and Montreal, there is no rail alternative,” said Tourisme Montréal spokeswoman Aurélie de Blois.

Mar 13, 2023 | jofskin.org | Nancy Messier |Feldan Therapeutics |Quebec Canada |Frédéric Couture

Main Article Content Keywords Basal Cell Carcinoma, BCC, Skin Cancer, Keratinocyte Cancer, KC, intralesional, intralesional injection, intralesional therapy, BCC mouse model, Feldan shuttle, ASO, antisense oligonucleotide, inducible NBCCS-like mouse model, mouse model, Gli1, FLD103 Abstract Introduction: Patients with nevoid basal cell carcinoma syndrome (NBCCS), also termed Gorlin syndrome, develop numerous basal cell carcinomas (BCCs). Current treatment options include systemic hedgehog...