Gary J. Bassell

Dec 19, 2023 | nature.com | Benjamin R. Rost |Gary J. Bassell |Wilfried Rossoll |Sebastian Diecke |Séverine Kunz

AbstractThe complex neuromuscular network that controls body movements is the target of severe diseases that result in paralysis and death. Here, we report the development of a robust and efficient self-organizing neuromuscular junction (soNMJ) model from human pluripotent stem cells that can be maintained long-term in simple adherent conditions.