Gefei Yu

Dec 5, 2024 | biorxiv.org | Abigail Thorpe |Qi Zeng |Erming Wang |Gefei Yu

AbstractAlzheimer's disease (AD) is the most common form of dementia, with approximately two-thirds of AD patients are females. Basic and clinical research studies show evidence supporting sex-specific differences contributing to the complexity of AD. There is also strong evidence supporting sex-specific interaction between the primary genetic risk factor of AD, APOE4 and AD-associated neurodegenerative processes.