Geoffrey N. Pronovost

Oct 6, 2023 | science.org | Guan-Hua Su |Susan Athey |Koon-Kiu Yan |Geoffrey N. Pronovost

MATERIALS AND METHODSThe objective of this study was to identify contributions of the maternal gut microbiome to placental development using gnotobiotic mouse models. In addition to characterization of placental phenotypes following microbiota depletion, we identified differentially regulated metabolites and evaluated whether these molecules modify placental deficiencies using in vivo and in vitro strategies.