Articles
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Mar 9, 2025 |
nature.com | George P. Patrinos
AbstractTacrolimus (TAC) is one of the most widely prescribed maintenance immunosuppressant drugs in solid organ transplantation. Kidney transplantation is often the preferred treatment for patients with the kidney failure and is complemented with TAC treatment. TAC treatment is often associated with adverse drug events, which can be reduced by pharmacogenomic (PGx)-guided prescription.
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Jan 21, 2025 |
mdpi.com | Aggeliki Liakopoulou |Sophia Letsiou |Konstantinos Avgoustakis |George P. Patrinos
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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May 14, 2024 |
nature.com | George P. Patrinos |Christina Mitropoulou
AbstractThe objective of this study was to estimate the cost-effectiveness of CYP3A5 genotype-guided tacrolimus dosing in kidney, liver, heart, and lung transplant recipients relative to standard of care (SOC) tacrolimus dosing, from a US healthcare payer perspective. We developed decision-tree models to compare economic and clinical outcomes between CYP3A5 genotype-guided and SOC tacrolimus therapy in the first six months post-transplant.
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Mar 26, 2024 |
mdpi.com | Stefanos Ferous |Nikolaos Siafakas |Fotini Boufidou |George P. Patrinos
All articles published by MDPI are made immediately available worldwide under an open access license. No specialpermission is required to reuse all or part of the article published by MDPI, including figures and tables. Forarticles published under an open access Creative Common CC BY license, any part of the article may be reused withoutpermission provided that the original article is clearly cited. For more information, please refer tohttps://www.mdpi.com/openaccess.
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Jan 30, 2024 |
pharmafocusasia.com | Marlo Möller |George P. Patrinos |Caitlin Uren
Author(s) : Marlo Moller, George P. Patrinos, Caitlin UrenBook Description:Population Genomics in the Developing World: Concepts, Applications, and Challenges, a new volume in the Translational and Applied Genomics series, provides a comprehensive, up-to-date summary of the field of population genomics in developing countries.
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