Georgina E. Lindop

Mar 10, 2024 | nature.com | Emma Wilson |Yizhou Yu |Nikolaos Patikas |Julien Prudent |L. Martins |Georgina E. Lindop | +1 more

AbstractOrganelles form membrane contact sites between each other, allowing for the transfer of molecules and signals. Mitochondria-endoplasmic reticulum (ER) contact sites (MERCS) are cellular subdomains characterized by close apposition of mitochondria and ER membranes. They have been implicated in many diseases, including neurodegenerative, metabolic, and cardiac diseases. Although MERCS have been extensively studied, much remains to be explored.