Gianluca Tedaldi

Nov 13, 2023 | frontiersin.org | Paul Ruff |Francesco Pepe |Gianluca Tedaldi

1 IntroductionColorectal cancer (CRC) is the third most common cancer worldwide (colon: 1,148,515; rectum: 732,210) (1) and the second leading cause of cancer-related deaths (colon: 935,000; rectum: 339,022) (2) in 2020. There were about 555,000 new cases of colorectal cancer in China in 2020, accounting for 12.2% of the number of new cancers in that year, and nearly 286,000 deaths, accounting for 9.5% of the number of cancer deaths in China that year (3).