Gilda Padalino

Jul 15, 2024 | biorxiv.org | Gilda Padalino |Katrina Duggan |Luis AJ Mur |Jean-Yves Millard

AbstractAntimicrobial resistance remains a global challenge threatening the ability to control diseases caused by bacterial infections. Here, we explored the antimicrobial activity of 2,3-N,N-diphenyl quinoxaline derivatives against representative Gram-positive, Gram-negative and Mycobacterium species.

Apr 24, 2024 | biorxiv.org | Mukul Rawat |Gilda Padalino |Tomas Yeo |Andrea Brancale

AbstractThe human pathogens Plasmodium and Schistosoma are each responsible for over 200 million infections annually, being particularly problematic in low- and middle-income countries. There is a pressing need for new drug targets for these diseases, driven by emergence of drug-resistance in Plasmodium and the overall dearth of new drug targets for Schistosoma.

Jul 21, 2023 | dx.doi.org | Matthias Schiedel |Gilda Padalino |Michael McDonough

Download Hi-Res ImageDownload to MS-PowerPointCite This:J. Med. Chem. 2023, XXXX, XXXMatthias SchiedelDepartment of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA, U.K., Darius J. B. McArdleDepartment of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA, U.K., Gilda PadalinoThe Department of Life Sciences (DLS), Aberystwyth University, Wales SY23 3DA, U.K., Anthony K. N.