Giulia Benevolo

Dec 29, 2023 | acsjournals.onlinelibrary.wiley.com | Francesca Palandri |Giuseppe Palumbo |Giulia Benevolo |Alessandra Iurlo

INTRODUCTION Myelofibrosis (MF) is the most severe among the classical Philadelphia-negative myeloproliferative neoplasm (MPN), which may present de novo (primary myelofibrosis [PMF]) or secondary to essential thrombocythemia/polycythemia vera (PET/PPV-MF, SMF).1, 2 It is clinically characterized by splenomegaly, systemic symptoms, and progressive cytopenias.