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Nov 7, 2024 | 
science.org | Gordon Rix |Julia Phan |Carsen Stringer |Noelia Martínez-Sánchez
PerspectivePhysiologyThe hepatic vagal nerve mediates the impact of circadian disruption on food intake in miceNoelia Martinez-Sanchez and David Ray Authors Info & AffiliationsAbstractTiming mechanisms have evolved across all kingdoms of life to anticipate daily changes in the light environment and to optimize opportunities for nutrition. In mammals, the central circadian clock in the hypothalamic suprachiasmatic nucleus synchronizes to external light.
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Nov 7, 2024 | 
science.org | Gordon Rix |Julia Phan |Carsen Stringer |Hao Jiang
Editor’s summaryThe search for mathematical nets that allow for the design and synthesis of multicomponent metal-organic frameworks (MOFs) has been simplified by the enumeration of a few hundred merged nets. Simpler two-component MOFs can be described with edge-transitive nets. Jiang et al. mapped node-net relations among 53 of these basic nets, and the shared features allowed the researchers to identify 353 more complex merged nets with multiple nodes and linkers.
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Nov 7, 2024 | 
science.org | Gordon Rix |Julia Phan |Carsen Stringer |Dawei Zhang
Editor’s summaryWet dog shakes (WDS) define a widespread behavior in hairy animals that is used to remove water and irritants from hairy skin. However, the mechanism triggering WDS remains to be fully elucidated. Using optogenetics and behavioral protocols, Zhang et al. showed in mice that WDS are triggered by Piezo2-mediated activation of unmyelinated C-fiber low-threshold mechanoreceptors synaptically coupled with spinoparabrachial neurons.
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Nov 7, 2024 | 
science.org | Gordon Rix |Julia Phan |Carsen Stringer |Ying Yin
Editor’s summaryThree-dimensional covalent organic frameworks (COFs) with a rare self-penetrated topology have both small pore sizes and ultrahigh surface areas that enable high volumetric storage of methane. Yin et al. used six-connected polyhedra and triangular molecules to create two imine-linked COFs with a pore size of 1.1 nanometers and avolumetric surface area of 1900 square meters per cubic centimeter.
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Nov 7, 2024 | 
science.org | Gordon Rix |Julia Phan |Carsen Stringer |Rob Dunn
Books et al. EcologyAn “entomo-artist” celebrates insects and their rich history with humankindGet full access to this articleView all available purchase options and get full access to this article. Books1The Insect Epiphany: How Our Six-Legged Allies Shape Human Culture Barrett Klein Timber Press, 2024. 368 pp.
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Nov 7, 2024 | 
science.org | Gordon Rix |Julia Phan |Carsen Stringer |Zhiyuan Chen
Editor’s summaryThe recent severe acute respiratory syndrome coronavirus pandemic has provided an unparallelled opportunity to analyze how associated public health measures and behavioral changes affected other globally distributed infections. Chen et al. used phylodynamics analysis on a combination of molecular, epidemiological, and travel data to find out what happened to influenza during the pandemic (see the Perspective by Rohani and Bahl).
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Nov 7, 2024 | 
science.org | Gordon Rix |Julia Phan |Carsen Stringer |Rory Williams
Editor’s summaryWe can extract intricate design principles underlying protein structure, function, and adaptation from patterns of conservation and change across natural homologs. However, nature took millions of years to generate rich sets of homologous gene sequences, effectively rendering them a nonrenewable resource. Rix et al. developed a high-error-rate orthogonal replication (OrthoRep) system that compresses extensive gene divergence into laboratory time frames at scale.
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Nov 7, 2024 | 
science.org | Gordon Rix |Julia Phan |Carsen Stringer
The reelection of Donald Trump for a second, nonconsecutive term as US president—mirroring only Grover Cleveland’s 22nd and 24th presidencies after the Civil War—underscores a reality: Although his success stems partly from a willingness to tap into xenophobia, sexism, racism, transphobia, nationalism, and disregard for truth, his message resonates with a large portion of the American populace who feel alienated from America’s governmental, social, and economic institutions.
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Nov 7, 2024 | 
science.org | Gordon Rix |Julia Phan |Carsen Stringer |Corinne N. Simonti
Conservation Looking beyond zoosCorinne SimontiPrivately owned tigers show levels of genetic diversity similar to those of wild tigers, suggesting their potential use in conservation. PHOTO: TIERFOTOAGENTUR/ALAMY STOCK PHOTOTigers, which include six subspecies, some of which are extinct in the wild, have experienced severe population declines in recent years.
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Nov 7, 2024 | 
science.org | Gordon Rix |Julia Phan |Carsen Stringer |Marius Pachitariu
Editor’s summaryRecent years have seen the development of a substantial number of new approaches to investigating the brain. Some of the most promising are techniques that allow functional recordings of large numbers of neurons with electrophysiological or optical imaging methods.
