Gregory Holste

Jul 6, 2024 | nature.com | Gregory Holste |Bobak J. Mortazavi

AbstractAdvances in self-supervised learning (SSL) have enabled state-of-the-art automated medical image diagnosis from small, labeled datasets. This label efficiency is often desirable, given the difficulty of obtaining expert labels for medical image recognition tasks. However, most efforts toward SSL in medical imaging are not adapted to video-based modalities, such as echocardiography.

Mar 15, 2024 | medrxiv.org | Evangelos Oikonomou |Gregory Holste |Andreas C. Coppi |Robert McNamara

R.K. is an Associate Editor of JAMA and receives research support, through Yale, from the Blavatnik Foundation, Bristol-Myers Squibb, Novo Nordisk, and BridgeBio. He is a coinventor of U.S. Provisional Patent Applications 63/177,117, 63/428,569, 63/346,610, 63/484,426, and 63/508,315, and a co-founder of Ensight-AI, Inc. R.K. and E.K.O. are co-founders of Evidence2Health, a health analytics company.

Aug 23, 2023 | academic.oup.com | Gregory Holste

Aortic stenosis (AS) is a chronic, progressive disease, and associated with morbidity and mortality.1,2 With advances in both surgical and transcatheter aortic valve replacement,3 there has been an increasing focus on early detection and management.4–6 The non-invasive diagnosis of AS can be made with hemodynamic measurements using Doppler echocardiography,2,7–10 but that requires dedicated equipment and skilled acquisition and interpretation.