Guangli Liu

Nov 5, 2024 | onlinelibrary.wiley.com | Wei Zhu |Han Wang |Bin Feng |Guangli Liu

1 Introduction Articular cartilage, which has limited self-healing capacity, is predominantly located at the extremities of mobile bones.[1] The degeneration of articular cartilage can lead to the onset of osteoarthritis (OA), a disease associated with significant clinical and socioeconomic burdens.[2, 3] Small chondral defects, frequently observed in OA patients, are critical contributors to disease progression.[4] The targeted repopulation of mesenchymal stem cells (MSCs) with chondrogenic...