Guangyu Wang

Jan 15, 2025 | nature.com | Hua Bai |Guangyu Wang |Cameron J. Nowell |Nicolas H Voelcker |Bo Peng |Lin Li

AbstractMitochondrial morphology and function are intrinsically linked, indicating the opportunity to predict functions by analyzing morphological features in live-cell imaging. Herein, we introduce MoDL, a deep learning algorithm for mitochondrial image segmentation and function prediction. Trained on a dataset of 20,000 manually labeled mitochondria from super-resolution (SR) images, MoDL achieves superior segmentation accuracy, enabling comprehensive morphological analysis.

Jan 2, 2025 | science.org | Weiwei Wang |Xianli Wang |Mike Flannigan |Luc Guindon |Tom Swystun |Wanli Wu | +2 more

Research ArticleWILDFIRESScience2 Jan 2025Vol 387, Issue 6729pp. 91-97 Access the full articleView all access options to continue reading this article. Supplementary MaterialsMaterials and MethodsSupplementary TextFigs. S1 to S20Tables S1 to S13References (56–89)References and Notes1M. Flannigan, A. S. Cantin, W. J. De Groot, M. Wotton, A. Newbery, L. M. Gowman, Global wildland fire season severity in the 21st century. For. Ecol. Manage. 294, 54–61 (2013). 2X. Wang, D. K. Thompson, G. A. Marshall, C. Tymstra, R.

Nov 21, 2024 | biorxiv.org | Guangyu Wang

AbstractTrikafta is well-known for correcting the thermal and gating defects caused by the most common cystic fibrosis mutation F508del in the human cystic fibrosis transmembrane conductance regulator even at physiological temperature. However, the exact pathway is still unclear.

Mar 26, 2024 | mdpi.com | Guangyu Wang

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Feb 28, 2024 | nature.com | Guangyu Wang

Correction to: Scientific Reports https://doi.org/10.1038/s41598-023-47100-0, published online 07 December 2023The original version of this Article contained errors. In the original version of this Article, the calculated heat capacity of homotetrameric TRPV3 was incorrectly calculated.