Guole Liu

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DeepETPicker: Fast and accurate 3D particle picking for cryo-electron tomography using weakly supervised deep learning - Nature Communications

Mar 6, 2024 | nature.com | Guole Liu |Mengxuan Qiu |Yun Zhu |Fei Sun

AbstractTo solve three-dimensional structures of biological macromolecules in situ, large numbers of particles often need to be picked from cryo-electron tomograms. However, adoption of automated particle-picking methods remains limited because of their technical limitations. To overcome the limitations, we develop DeepETPicker, a deep learning model for fast and accurate picking of particles from cryo-electron tomograms.

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