Gyujoon Hwang

Mar 22, 2024 | nature.com | Junhao Wen |Bingxin Zhao |Guray Erus |Elizabeth Mamourian |Gyujoon Hwang |Jingxuan Bao | +5 more

AbstractThe complex biological mechanisms underlying human brain aging remain incompletely understood. This study investigated the genetic architecture of three brain age gaps (BAG) derived from gray matter volume (GM-BAG), white matter microstructure (WM-BAG), and functional connectivity (FC-BAG). We identified sixteen genomic loci that reached genome-wide significance (P-value < 5×10−8).