Haci Mehmet Kayili

Jul 14, 2023 | frontiersin.org | Stevan Springer |Stacy A. Malaker |Haci Mehmet Kayili

IntroductionImmune surveillance is a critical mechanism employed by our immune system to monitor for and protect against foreign agents posing health threats. The major histocompatibility complex (MHC) class I (MHC-I) and class II (MHC-II) molecules present repertoires of immunopeptides on the surface of cells, the immunopeptidome, by which T-cells can recognise abnormal or foreign peptide antigens, such as those of pathogen origin (1).