Hai Wei

Oct 28, 2024 | nature.com | Hai Wei |Yi M. Weaver |Benjamin Weaver

AbstractCaspases regulate and execute a spectrum of functions including cell deaths, non-apoptotic developmental functions, and stress responses. Despite these disparate roles, the same core cell-death machinery is required to enzymatically activate caspase proteolytic activities. Thus, it remains enigmatic how distinct caspase functions are differentially regulated.