Haiyan Liu

Sep 10, 2024 | nature.com | Haiyan Liu

D-proteins hold considerable potential in biotechnological applications because of their generally anticipated higher bioorthogonality and stability over L-proteins. In a recent paper in Cell Research, Sun and colleagues demonstrated the successful design of de novo D-proteins that selectively bind to specific target regions of natural L-proteins or L-peptides. Unlike natural 'proteins composed of L-amino acid residues, D-proteins are built of D-amino acid residue units.

May 10, 2024 | mdpi.com | Lin Ye |Xiaohui Chen |Haiyan Liu |Ran Zhang

1. IntroductionWith the rapid growth of international trade and global logistics needs, the maritime industry has become an important force driving the global economy. However, the development of the maritime industry has also brought about a series of related issues, such as maritime safety management, marine environmental protection, and other challenges [1,2,3]. In this context, a large amount of automatic identification system (AIS) data provides valuable support for related research.

May 31, 2023 | frontiersin.org | Three Gorges |Javier Moreno |Xun Sun |Haiyan Liu

1 IntroductionVisceral leishmaniasis (VL), also known as kala-azar, is a zoonotic parasitic disease caused by protozoan Leishmania parasites, mainly transmitted by the bite of female phlebotomine sandflies (Gebresilassie et al., 2015; Lévêque et al., 2020). According to the WHO, leishmaniasis is endemic in nearly 98 countries of tropical and subtropical regions, primarily affecting developing countries (Alvar et al., 2012).