Han Leng Ng

Aug 22, 2024 | nature.com | Balraj S. Sandhar |Jack Keane |Hazel Blythe |Aled Jones |Silvia Fanti |Mirjana Efremova | +5 more

AbstractAtrial fibrillation (AF) is the most common sustained arrhythmia and carries an increased risk of stroke and heart failure. Here we investigated how the immune infiltrate of human epicardial adipose tissue (EAT), which directly overlies the myocardium, contributes to AF. Flow cytometry analysis revealed an enrichment of tissue-resident memory T (TRM) cells in patients with AF.

Jan 31, 2024 | onlinelibrary.wiley.com | Mark Robinson |Philippa May |Andrew Innes |Han Leng Ng

INTRODUCTION Myeloid leukaemia is the most prevalent haematological malignancy in individuals aged over 65, with UK annual incidence rates in this age group of 20 per 100 000 and 7.8 per 100 000 for acute myeloid leukaemia (AML) and chronic myeloid leukaemia (CML) respectively.1 CML comprises two phases; chronic phase (CP), which is the most common phase at diagnosis, and now has a near normal life expectancy for those who respond to therapy,2 and blast phase (BP), characterised by increased...