Hana Janova

Nov 1, 2024 | jci.org | Joel C. Bornstein |Hana Janova |Thaddeus S. Stappenbeck |Michael Diamond

AbstractLoss of enteric neurons leading to long-term gastrointestinal dysfunction is common to many diseases, and the path to functional recovery is unclear. In this issue of the JCI, Janova et al. report that West Nile virus killed enteric neurons and glia via CD4+ and CD8+ T cells acting through the perforin and Fas ligand pathways. Enteric glial cells contributed to neurogenesis and at least partial replacement of affected neurons.

Aug 29, 2024 | jci.org | Hana Janova |Fang Zhao |Pritesh Desai |Matthias Mack

ResearchGastroenterologyInfectious diseaseOpen Access | 10.1172/JCI181421 J Clin Invest. https://doi.org/10.1172/JCI181421. Copyright © 2024, Janova et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.