Haolong Li

Jun 9, 2023 | frontiersin.org | Siqi Huang |Xiaojun Liu |Yuqi Yang |Haolong Li

1 IntroductionGastric cancer (GC) is the fifth most common cancer type and the third leading cause of death worldwide (1). The major risk factors for GC include Helicobacter pylori infection, age, high salt intake, and decreased intake of fruits and vegetables (2). Chronic H. pylori infection is the main reason for GC, accounting for approximately 89% of the distal GC cases worldwide (3). At present, >1 million people worldwide are newly diagnosed with GC each year.