Haoxing Xu

Nov 14, 2024 | cell.com | Liangzhu Laboratory |Haoxing Xu

KeywordscGASSTINGTFEBlysosomeGet full text accessLog in, subscribe or purchase for full access. References1. Liu, S. ... Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activationScience. 2015; 347, aaa26302. Wang, A. ... Innate immune sensing of lysosomal dysfunction drives multiple lysosomal storage disordersNat. Cell Biol. 2024; 26:219-2343. Ballabio, A. ∙ Bonifacino, J.S.Lysosomes as dynamic regulators of cell and organismal homeostasisNat. Rev. Mol. Cell Biol.

Nov 27, 2023 | nature.com | Haoxing Xu

Two DNA nanodevices, RatiNa and pHlicker, provide precise mapping of sodium levels in acidic organelles and potassium activity at a single-organelle resolution. Sodium and potassium ions are crucial for governing cell physiology through the regulation of steep concentration gradients across the plasma membrane, ultimately determining membrane potential (Δψ).