JACC Specialty Journals

3 weeks ago | jacc.org | Andrew Chang |Joel D. Kaufman |Annabel Tan |Sanjiv Shah

References1. "Global burden of 87 risk factors in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019". Lancet . 2020;396:1223-1249. 2. "Global association of air pollution and heart failure: a systematic review and meta-analysis". Lancet . 2013;382:1039-1048. 3. "The Cardiovascular Health Study: design and rationale". Ann Epidemiol . 1991;1:263-276. 4.

3 weeks ago | jacc.org | Aderonke T Abiodun |Chengsheng Ju |Catherine Welch |Jennifer Lai

Introduction Fluoropyrimidine chemotherapy agents are used first line in the treatment of many gastrointestinal and other solid organ malignancies globally.1-3 The development of cardiotoxicity can often complicate its use and has various manifestations from asymptomatic electrocardiogram changes to angina, heart failure (HF), myocardial infarction, and sudden cardiac death.4 Baseline cardiovascular disease (CVD) and cardiovascular risk factors are common in patients with gastrointestinal...

1 month ago | jacc.org | Harlan M. Krumholz

IntroductionWorld history has its cycles. Now, we are experiencing rising tensions among and within countries. Geopolitical issues dominate the news. For some, international travel is becoming fraught. Economic policies are trending toward isolationism, and globalism appears on the decline. Moreover, the pace of change is accelerating.

1 month ago | jacc.org | Daniel Johnson |Michael Liu |Victoria Bartlett |Zhaonian Zheng

References1. "Monetizing Medicine: Private Equity and Competition in Physician Practice Markets. American Antitrust Institute, Petris Center". Washington Center for Equitable Growth, 2023. 2. "Private equity–acquired physician practices and market penetration increased substantially, 2012–21". Health Aff . 2024;43:3: 354-362. https://doi.org/10.1377/hlthaff.2023.00152. 3. "Changes in hospital adverse events and patient outcomes associated with private equity acquisition". JAMA . 2023;330:24: 2365-2375.

1 month ago | jacc.org | Daniel Morris |Chung-Lieh Hung |Tor Biering-Sørensen |Tatiana Kuznetsova

Introduction Two-dimensional (2D) left ventricular (LV) global longitudinal systolic strain (GLS), with the use of 2D transthoracic speckle-tracking echocardiography (STE), is a sensitive parameter for detecting early or subclinical LV systolic dysfunction, even when left ventricular ejection fraction (LVEF) is preserved.1-3 However, some important issues concerning GLS remain uncertain, such as the cutoff of the lower limit of the reference normal range (LLN) of GLS for each ultrasound...