Hazuki Takahashi

Oct 31, 2024 | biorxiv.org | Callum J. C. Parr |Hazuki Takahashi |Matthew Valentine |Kayoko Yasuzawa

AbstractLong-read sequencing has emerged as a powerful tool for uncovering novel transcripts and genes. However, existing protocols often lack confidence in identifying the transcription start site (TSS) and fail to capture non-poly(A) RNA, thereby limiting the discovery of novel genes, particularly long non-coding RNAs (lncRNAs).

Feb 21, 2024 | nature.com | Stefano Gustincich |Hazuki Takahashi

AbstractRNA structure folding largely influences RNA regulation by providing flexibility and functional diversity. In silico and in vitro analyses are limited in their ability to capture the intricate relationships between dynamic RNA structure and RNA functional diversity present in the cell.