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Nov 13, 2024 | 
veterinaryresearch.biomedcentral.com | Henan Academy
MARC-145, human embryonic kidney 293 T (HEK-293 T), CRL-2843-CD163, and human cervix carcinoma HeLa cells were stored in our laboratory [27]. CRL-2843-CD163 cells were maintained in Roswell Park Memorial Institute 1640 medium (Cat. No. 31800; Solarbio), supplemented with 10% heat-inactivated fetal bovine serum (FBS; Cat. No. 10270–106; Gibco) and antibiotics (100 U/mL penicillin, 100 mg/mL streptomycin; Cat. No. P1400; Solarbio) in a humidified 37 °C and 5% CO2 incubator.
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Aug 23, 2024 | 
academic.oup.com | Henan Academy
Molecular representation learning is pivotal for advancing deep learning applications in quantum chemistry and drug discovery. Existing methods for molecular representation learning often fall short of fully capturing the intricate interactions within chemical bonds of 2D topological graphs and the multifaceted effects of 3D geometric conformations.
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Aug 22, 2024 | 
molecular-cancer.biomedcentral.com | Henan Academy
The workflow of our molecular analysis and modeling for both the training (n = 189) and validation (n = 184) cohorts is depicted in Fig. 1. The age and sex ratio were balanced for CRC and healthy groups in the training cohort to reduce the impact of potential confounding factors. The training cohort included 93 CRC patients and 96 healthy individuals (Table S1).
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Aug 12, 2024 | 
link.aps.org | Huihui Yu |Yuan Zhang |Henan Academy |Qilong Wu
Abstract In this Letter, we use quantum trajectory theory to simulate heterodyne detection of narrow bandwidth superradiant lasing from an incoherently excited atomic ensemble. To this end, we describe the system dynamics and account for stochastic measurement backaction by second-order mean-field theory. Our simulations show how heterodyne measurements break the phase symmetry, and initiate the atomic coherence with a random phase and a long temporal phase coherence.
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May 26, 2024 | 
link.springer.com | Henan Academy |Henan Agricultural
AbstractCamelina sativa oil (CSO) and Semen Ziziphi Spinosae oil (SZSO) are functional oils that have beneficial effects on brain health. This study evaluated the sedative and hypnotic effects of vegetable oils with various n − 6/n − 3 polyunsaturated fatty acids (PUFA) ratios and ɑ-linolenic acid (ALA) contents to mice.
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May 10, 2024 | 
molecular-cancer.biomedcentral.com | Henan Academy
Y.J. had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Concept and design: Y.J. and S.G. Acquisition, analysis, or interpretation of data: All authors. Drafting of the manuscript: All authors.
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May 9, 2024 | 
link.springer.com | Henan Academy
AbstractAccurate presurgical prediction of pathological complete response (pCR) can guide treatment decisions, potentially avoiding unnecessary surgeries and improving the quality of life for cancer patients. We developed a minimal residual disease (MRD) profiling approach with enhanced sensitivity and specificity for detecting minimal tumor DNA from cell-free DNA (cfDNA). The approach was validated in two independent esophageal squamous cell carcinoma (ESCC) cohorts.
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Apr 28, 2024 | 
bmcpublichealth.biomedcentral.com | Henan Academy
The public benefits significantly from the information presented in high-quality and engaging TikTok videos related to myopia. In our study, we explored the impact of search strategy and sample size on video quality and audience engagement. Interestingly, we found that these two factors influenced audience engagement but did not affect video quality. Furthermore, specific characteristics of the videos emerged as potential contributors to both video quality and audience engagement.
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Apr 11, 2024 | 
bmcpublichealth.biomedcentral.com | Henan Academy
In 2019, there were an estimated 3.87 million (95% UI: 332.70-446.79) incident CVD cases among individuals aged 15–39 years worldwide and the ASIR was 129.85 per 100 000 (95% CI: 102.60, 160.31). The highest ASIRs were seen in low SDI and low-middle SDI. (Table 1). The countries with higher ASIR were mainly distributed in sub-Saharan Africa, Central Asia, Western Asia, and northern part of East Asia. (Fig. 1).
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Feb 17, 2024 | 00149-9&sz=64)
cell.com | Henan Academy
Highlights • LsIMPDH expression is downregulated in RSV-infected SBPH, which decreases GTP content • Upregulation of LsMETTL3 by RSV results in an increase in m6A on LsIMPDH mRNAs • Recognition of m6A in LsIMPDH mRNAs by LsYTHDF3 promotes decay of LsIMPDH transcripts • Lower GTP limits viral replication in SBPH, leading to inefficient transmission Summary The titer of viruses that persist and propagate in their insect vector must be high enough for transmission yet not harm the insect, but...
