Henry Ng

May 16, 2024 | digitalcommons.library.tmc.edu | Mary E Tinetti |Ardeshir Hashmi |Henry Ng |Margaret Doyle

IMPORTANCE: Older adults with multiple conditions receive health care that may be burdensome, of uncertain benefit, and not focused on what matters to them. Identifying and aligning care with patients' health priorities may improve outcomes. OBJECTIVE: To assess the association of receiving patient priorities care (PPC) vs usual care (UC) with relevant clinical outcomes.

Feb 29, 2024 | biorxiv.org | Henry Ng |Armin N. Adly |Raymond T. Suhandynata |Devon H. Whelpley

AbstractCell cycle progression is governed by complexes of the cyclin-dependent kinases (CDKs) and their regulatory subunits cyclin and Cks1. CDKs phosphorylate hundreds of substrates, often at multiple sites. Multisite phosphorylation depends on Cks1, which binds initial priming phosphorylation sites to promote secondary phosphorylation at other sites. Here, we describe a similar role for a recently discovered phosphate-binding pocket (PP) on B-type cyclins.