-
Dec 21, 2024 | 
acrjournals.onlinelibrary.wiley.com | Ilaria Maccora |Hermine I Brunner |Amy Cassedy |Mekibib Altaye |Megan Quinlan‐Waters |Daniel Lovell | +2 more
INTRODUCTION Juvenile dermatomyositis (JDM) is a rare autoimmune disease characterized by symmetric proximal muscle weakness, a characteristic rash, and a risk for calcinosis.1, 2 Systemic immunosuppression is generally needed for JDM treatment to avoid severe disability and a decreased quality of life.1, 3, 4 Standard treatment includes corticosteroids (intravenous and oral), intravenous immunoglobulin (IVIG), methotrexate, and hydroxychloroquine.1, 5, 6 However, not all patients respond to...
-
Nov 15, 2024 | 
acrjournals.onlinelibrary.wiley.com | Hermine I Brunner |Anna Shmagel |Gerd Horneff |Ivan Foeldvari
Supporting Information Filename Description acr25465-sup-0001-Disclosureform.pdfPDF document, 1.7 MB Disclosure Form acr25465-sup-0002-Supinfo.pdfPDF document, 290.8 KB Appendix S1: Supporting Information
-
Nov 1, 2024 | 
jrheum.org | Hermine I Brunner |Cesar Pacheco-Tena |Ingrid Louw |Gabriel Vega-Cornejo
RESULTSParticipant disposition and baseline characteristics. Of the 127 participants included in the GO-VIVA main study primary analysis set,7 112/127 (88.2%) continued into the LTE, 71/127 (55.9%) completed IV golimumab dosing at week 244, and 69/127 (54.3%) completed follow-up at week 252 (Figure 1). AEs were the most common reason for discontinuation through week 252, accounting for 24 of the 127 (18.9%) LTE participants.
-
Aug 12, 2024 | 
acrjournals.onlinelibrary.wiley.com | Ekemini A. Ogbu |Hermine I Brunner |Esraa M Eloseily |Yonatan Butbul Aviel
INTRODUCTION Juvenile idiopathic arthritis (JIA) is among the most common chronic rheumatic diseases of childhood.
-
Aug 8, 2024 | 
jrheum.org | Hermine I Brunner |Cesar Pacheco-Tena |Ingrid Louw |Gabriel Vega-Cornejo
Intravenous Golimumab in Children With Polyarticular-Course Juvenile Idiopathic Arthritis: Long-Term Extension of an Open-Label, Phase III Study Hermine I. Brunner, César Pacheco-Tena, Ingrid Louw, Gabriel Vega-Cornejo, Ekaterina Alexeeva, Simone Appenzeller, Vyacheslav Chasnyk, Thomas Griffin, Carmen Navarrete Suarez, Sheila Knupp-Oliveira, Andrew Zeft, Yonatan Butbul Aviel, Deirdre De Ranieri, Beth S. Gottlieb, Deborah M. Levy, C.
-
Jul 26, 2024 | 
jrheum.org | Hermine I Brunner |Cesar Pacheco-Tena |Ingrid Louw |Gabriel Vega-Cornejo
Intravenous Golimumab in Children with Polyarticular-Course Juvenile Idiopathic Arthritis: Long-term Extension of an Open-label, Phase 3 Study Hermine I. Brunner, César Pacheco-Tena, Ingrid Louw, Gabriel Vega-Cornejo, Ekaterina Alexeeva, Simone Appenzeller, Vyacheslav Chasnyk, Thomas Griffin, Carmen Navarrete Suarez, Sheila Knupp-Oliveira, Andrew Zeft, Yonatan Butbul Aviel, Deirdre De Ranieri, Beth S. Gottlieb, Deborah M. Levy, C.
-
Jun 7, 2024 | 
ard.bmj.com | Hermine I Brunner |Jonathan Akikusa |Eslam Al-Abadi |John F. Bohnsack
A summary of AEs is presented in table 2. During 700 patient-years of follow-up, there were 1213 reported AEs and 201 of 225 (89.3%) patients experienced ≥1 AE. The most common AEs were upper respiratory tract infection (48 patients (21.3%)), JIA exacerbation (28 patients (12.4%)) and nasopharyngitis (27 patients (12.0%)). There were 39 serious AEs reported, and 34 of 225 (15.1%) patients experienced ≥1 serious AE.
-
Feb 9, 2024 | 
scienceblog.cincinnatichildrens.org | Hermine I Brunner |Prasad Devarajan
Research By:
Hermine Brunner, MD, MSc, MBA | Prasad Devarajan, MD
clinical trialsvideo
Hermine Brunner, MD, MSc, MBA, professor and director of Cincinnati Children’s Division of Rheumatology, is featured in a recent episode of the Greater Ohio Chapter of the Lupus Foundation of America’s podcast, My Lupus Living Room.
-
Sep 26, 2023 | 
acrjournals.onlinelibrary.wiley.com | Robert C. Brucia |Kristen Hayward |Hermine I Brunner |Maricarmen Lopez-Pena
INTRODUCTION The scope of clinical practice of pediatric rheumatology is broad and includes multisystem diseases, inflammatory diseases affecting specific organs or anatomical sites (eg, arthritis, uveitis, autoimmune encephalitis), autoinflammatory conditions, and musculoskeletal pain syndromes.
-
Sep 13, 2023 | 
healio.com | Rob Volansky |Shenaz Bagha |Hermine I Brunner
Source/Disclosures Source: Brunner H. What’s New in Pediatric Rheumatology? Presented at The Congress of Clinical Rheumatology West; Sept. 7-10, 2023 (hybrid meeting). Disclosures: Brunner reports consulting fees from Aurinia, AbbVie, AstraZeneca-Medimmune, Biogen, Boehringer, Bristol-Myers Squibb, Celgene, Eli Lilly & Co., EMD Serono, GlaxoSmithKline, F.
