
Hong Ryul Jin
Articles
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Jan 17, 2025 |
arxiv.org | Hong Ryul Jin
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Oct 28, 2024 |
pubs.acs.org | Hong Ryul Jin |Lanlan Yao |Wenjing Chen |Tao Hou
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Oct 28, 2024 |
dx.doi.org | Hong Ryul Jin |Lanlan Yao |Wenjing Chen |Tao Hou
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Apr 21, 2024 |
biorxiv.org | Christopher Hawk |Hong Ryul Jin
AbstractMaintaining proper protein homeostasis is essential for cell physiology. The ribosome and GTPases, which are two of the most ancient and critical cellular molecules, are central players in protein synthesis and its regulation. Here we report the discovery of a new general translation factor that targets stalled ribosomes and promotes protein synthesis in an evolutionarily conserved manner.
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Feb 3, 2024 |
biorxiv.org | Hong Ryul Jin |Xin Chen
AbstractThe widespread distribution of pseudouridine (Ψ), an isomer of the canonical uridine base, in RNA indicates its functional importance to the cell. In eukaryotes, it is estimated that around 2% of ribosomal RNA nucleotides are pseudouridines, most of which are located in functional regions of the ribosome. Defects in RNA pseudouridylation induce a range of detrimental effects from compromised cellular protein biosynthesis to disease phenotypes in humans.
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