Hong-Su Park

May 13, 2024 | journals.plos.org | Megan Levy |Jessica Chen |Jaclyn A Kaiser |Hong-Su Park |PLOS Pathogens

Loading metrics Open Access Peer-reviewedResearch Article ? This is an uncorrected proof. Citation: Levy M, Chen JW, Kaiser JA, Park H-S, Liu X, Yang L, et al. (2024) Intranasal respiratory syncytial virus vaccine attenuated by codon-pair deoptimization of seven open reading frames is genetically stable and elicits mucosal and systemic immunity and protection against challenge virus replication in hamsters. PLoS Pathog 20(5): e1012198.

Apr 25, 2024 | nature.com | Christine Nelson |Hong-Su Park |Cindy Luongo |Shirin Munir |Peter D. Kwong |Kennichi Dowdell | +3 more

AbstractImmunization via the respiratory route is predicted to increase the effectiveness of a SARS-CoV-2 vaccine. Here, we evaluate the immunogenicity and protective efficacy of one or two doses of a live-attenuated murine pneumonia virus vector expressing SARS-CoV-2 prefusion-stabilized spike protein (MPV/S-2P), delivered intranasally/intratracheally to male rhesus macaques.