Hongcheng Cheng

Dec 4, 2024 | cell.com | Yajing Qiu |Yapeng Su |Ermei Xie |Hongcheng Cheng |Jing Du |Yue Xu | +6 more

References1. Chow, A. ∙ Perica, K. ∙ Klebanoff, C.A. ... Clinical implications of T cell exhaustion for cancer immunotherapyNat. Rev. Clin. Oncol. 2022; 19:775-7902. Rudloff, M.W. ∙ Zumbo, P. ∙ Favret, N.R. ... Hallmarks of CD8(+) T cell dysfunction are established within hours of tumor antigen encounter before cell divisionNat. Immunol. 2023; 24:1527-15393. Fenwick, C. ∙ Joo, V. ∙ Jacquier, P. ... T-cell exhaustion in HIV infectionImmunol. Rev. 2019; 292:149-1634. Fisicaro, P. ∙ Barili, V. ∙ Montanini, B. ...

Nov 1, 2024 | jitc.bmj.com | Yapeng Su |Yajing Qiu |Ermei Xie |Hongcheng Cheng

Regular and Young Investigator Award AbstractsCellular Therapies 230 Mannose supplementation: a strategy for metabolically driving a stem-like T cell program for improved tumor control Statistics from Altmetric.com Request Permissions If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service.

Nov 1, 2024 | dx.doi.org | Yapeng Su |Yajing Qiu |Ermei Xie |Hongcheng Cheng

Regular and Young Investigator Award AbstractsCellular Therapies 230 Mannose supplementation: a strategy for metabolically driving a stem-like T cell program for improved tumor control Request Permissions If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Jul 6, 2023 | embopress.org | Tian Zhao |Jiaojiao Zhang |Yuanyuan Meng |Hongcheng Cheng

Mitochondrial biogenesis is the process of generating new mitochondria to maintain cellular homeostasis. Here, we report that viruses exploit mitochondrial biogenesis to antagonize innate antiviral immunity. We found that nuclear respiratory factor-1 (NRF1), a vital transcriptional factor involved in nuclear-mitochondrial interactions, is essential for RNA (VSV) or DNA (HSV-1) virus-induced mitochondrial biogenesis.