Hongjie Xia

Dec 10, 2023 | nature.com | Ching-Lin Hsieh |Andrew Horton |Xuping Xie |Hongjie Xia |Pei-Yong Shi |Andrew D Ellington | +7 more

AbstractThe ongoing evolution of SARS-CoV-2 into more easily transmissible and infectious variants has provided unprecedented insight into mutations enabling immune escape. Understanding how these mutations affect the dynamics of antibody-antigen interactions is crucial to the development of broadly protective antibodies and vaccines. Here we report the characterization of a potent neutralizing antibody (N3-1) identified from a COVID-19 patient during the first disease wave.