Honglin Xia

Jun 26, 2024 | onlinelibrary.wiley.com | Fan Li |Fulong Zhang |Haiwang Shi |Honglin Xia

Introduction One of the hallmarks of mammalian aging is the diminished regenerative potential of tissues.1 Skeletal muscle relies on muscle stem cells (MuSCs), or satellite cells, for regeneration. Positioned between the sarcolemma and basal lamina of muscle fibres, MuSCs are activated during postnatal myogenesis through myo-trauma, exercise or stress, leading to the formation of myoblasts.