Horacio Cárdenas

Feb 18, 2025 | insight.jci.org | JCI Insight |Andres R. Valdivia |Andrés Reyes Valdivia |Horacio Cardenas |Horacio Cárdenas |Ana Isac

ResearchCell biologyOncologyOpen Access | 10.1172/jci.insight.184935 JCI Insight. https://doi.org/10.1172/jci.insight.184935. Copyright © 2025, Valdivia et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. View PDF AbstractThe omentum is the primary site of metastasis for ovarian cancer (OC).

Jan 23, 2024 | onlinelibrary.wiley.com | Yinu Wang |Andrea E. Calvert |Horacio Cardenas |Horacio Cárdenas |Jonathon S. Rink

1 Introduction Emergence of platinum (Pt) resistance (Pt-R) predicts invariably fatal outcomes in high grade serous ovarian cancer (HGSOC) with an expected median survival of 12–18 months.[1, 2] Pt-R HGSOC remains an area of unmet need, where progress has remained slow and clinical outcomes are lagging.[3-6] Understanding key vulnerabilities of Pt-R OC could unlock new possibilities to target HGSOC and improve survival.