Howard L. Kaufman

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Articles

Cryoablation and post-progression immune checkpoint inhibition in metastatic melanoma: a phase II trial - Nature Communications

Aug 26, 2024 | nature.com | Meghan J. Mooradian |Florian J. Fintelmann |Thomas LaSalle |Alexander Graur |Sophia Z. Shalhout |Howard L. Kaufman | +4 more

AbstractImage-guided percutaneous cryoablation is an established minimally invasive oncologic treatment. We hypothesized that cryoablation may modify the immune microenvironment through direct modulation of the tumor, thereby generating an anti-tumor response in tumors refractory to immune checkpoint inhibition (ICI).

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